 Pedro J. del Nido, MD
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Departments/Divisions
Cardiac Surgery
Cardiovascular Program
Transplantation
Specialties
aortic and mitral valve reconstruction
cardiovascular surgery
minimally invasive surgery (PDA + vasc ring)
robotic surgery
Services/Programs
Aero-Digestive Disorders (CADD), Center for
Cardiac Surgery Program
Heart Transplant Program
Robotic Surgery, Center for
Clinical Titles
Chairman, Department of Cardiac Surgery
Senior Associate in Cardiac Surgery
Academic Appointment
William E. Ladd Professor of Child Surgery, Harvard Medical School
Board Certification(s)
Surgery, Thoracic Surgery
Language(s)
Spanish
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Medical/Dental School
University of Wisconsin Medical School, Madison, WI (1977)
Internship
General Surgery, Boston University, Boston, MA (07/78 to 06/82)
Residency
Toronto General Hospital, Toronto, CANADA (07/83 to 06/85)
Fellowship
Hospital for Sick Children, Toronto, CANADA (07/85 to 06/86)
NARRATIVE REPORT OF RESEARCH, TEACHING AND CLINICAL CONTRIBUTIONS
My laboratory research work has focused on two areas related cardiac surgery:
The first area involves investigation of mechanisms responsible for the development of heart failure in hypertrophy. Currently, my work includes: investigation of mechanisms responsible for decreased tolerance to ischemia in hypertrophied myocardium and the role angiogenesis plays in progression of hypertrophy to heart failure.
The second area of investigation aims to develop techniques for performing reconstructive surgery inside the beating heart using 3-D echocardiography. This project is a research partnership between ourselves, two engineering laboratories and industry and proposes to design and implement new technology and instrumentation to facilitate repair of intracardiac defects in the beating heart, thus obviating the need for open heart surgery.
My teaching activities include supervising pre- and post-doctoral research fellows working in my laboratory and instructing clinical residents and fellows in pediatric cardiac surgery. I actively participate in didactic conferences covering laboratory and clinical investigation, and in continuing medical education courses organized by the Departments of Pediatric Cardiology and Pediatric Cardiac Surgery.
My clinical activities include performing surgical procedures to repair all forms of congenital heart defects in children and adults. Other surgical procedures I perform include heart transplantation and mechanical circulatory support of children in end-stage heart failure. I have also developed techniques for performing minimally invasive cardiac surgery to correct simple and complex heart cardiac defects in infants and children.
FUNDING INFORMAITON (* active grants)
2003-2008* National Institutes of Health (NHLBI)
Principal Investigator
Image Guided Intracardiac Beating Heart Surgery
Bioengineering Research Partnership
(RO1 HL073647)
2004-2009* National Institutes of Health (NHLBI)
Principal Investigator
Angiogenesis, Cardiac Hypertrophy and Surgical Ischemia
(RO1 HL63095)
REPORT OF CURRENT RESEARCH ACTIVITIES
Image Guided Intracardiac Beating Heart Surgery
This a Bioengineering Research Partnership to develop novel imaging techniques and instrument modification for performing reconstructive surgery inside the beating heart. The partnership includes two engineering laboratories (Dupont-Boston U.; Howe-Harvard DEAS), and industry (Philips Medical Systems) working on modification of ultrasound imaging hardware, image processing, instrument modification, and device development.
Role – Principal Investigator
Angiogenesis, Cardiac Hypertrophy and Surgical Ischemia
This project aims to study the role of Hypoxia Inducible factor in capillary growth during the progression of pressure overload hypertrophy.
Role – Principal Investigator.
Pedro del Nido, MD, Research site
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